Oct 15, 2018 · The results showed that the risk of prostate cancer rose along with rising PSA levels, regardless of age. even PSA levels within a normal range still showed an increased risk for prostate cancer. PSA level is high (>10 ng/mL) or if there is high grade disease on TRUS biopsy (Gleason score >7), lymph node sampling is usually performed at the time the patient undergoes surgery (radical retropubic prostatectomy). Table 1. Age reference range for PSA Age PSA in ng/mL 40–49 years <2.5 50–59 years <3.5 60–69 years <4.5 70+ years <6.5 Mar 12, 2014 · Screening may be considered in men ages 55 to 69 with the knowledge that it will prevent about one cancer death for every 1,000 men screened. Expert guidelines don't recommend PSA screening in men 70 and older. Because of their more limited lifespan, these men are less likely to benefit from early detection of low-risk cancer. Age-specific PSA thresholds for people with possible symptoms of prostate cancer. Age (years) Prostate-specific antigen threshold (micrograms/litre) Below 40. Use clinical judgement. 40 to 49. More than 2.5. 50 to 59. More than 3.5. According to a review of studies, the normal ranges for total PSA in nanograms per milliliter (ng/mL) are: age 49 or younger: 0.0–2.5 ng/mL. age 50 to 59: 0.0–3.5 ng/mL. age 60 to 69: 0.0–4.5 ng/mL. age 70 or older: 0.0–6.5 ng/mL. When total PSA levels are higher than the appropriate range, a person has an increased risk for prostate In general, low-risk or normal results are less than 2.0 ng/mL while PSA levels ranging from 2.0 to 10.0 ng/mL are considered to be in the "gray zone". The gray zone indicates the biopsy decision is not black or white and must be considered carefully. Patients with PSA levels in the gray zone can benefit from the ExoDx TM Prostate Test which Apr 11, 2023 · There is no specific normal or abnormal level of PSA because factors such as age and ethnicity make it hard for researchers to establish a normal range. However, most doctors consider PSA levels of 4.0 ng/ml as high and would often recommend a prostate biopsy. One study shows that men with this level of PSA often have prostate cancer. Low PSA May 8, 2018 · The CAP trial was a cluster randomized trial in the United Kingdom among 415,357 men aged 50 to 69 years invited for a single PSA-based screening for prostate cancer. 12 Men with a PSA level of 3.0 ng/mL or greater were referred for biopsy. Men with localized prostate cancer were offered enrollment into the Prostate Testing for Cancer and Sep 1, 2010 · A simple blood test performed at age 60 can determine a man's risk of dying from prostate cancer within the next 25 years, according to a new study led by Memorial Sloan Kettering Cancer Center investigators. The study's findings suggest that regular prostate-specific antigen (PSA) screening for prostate cancer should be focused on men who receive high readings from a PSA test performed at age The test detects the prostate-specific antigen, which is a protein produced by cells in the prostate gland, both normal and malignant cells. Men who have prostate cancer often have elevated PSA levels. A blood sample is taken for analysis and results are read as nanogram of PSA per milliliter of blood (ng/mL). The PSA test was first approved by U36Gv.